Abstract: Objective To investigate the drugs used in elderly cardiovascular disease patients． Methods Nine hundred and thirty prescriptions for 523 elderly cardiovascular disease patients adm itted to our department in November 2013 were analyzed． Results The mean age of the patients was 77．35±10．14 years． The average number of diagnosed cardiovascular diseases in each patient was 2．50±0．91． Those who were diagnosed with 3 cardiovascular diseases accounted for 47．6%． The top 3 diagnosed diseases were dyslipidem ia, hypertension and coronary heart disease． The number of drugs used in prescriptions for each patient was 4．98±2．31．The number of patients with their prescribed drugs≥5 accounted for 39．96% of the investigated patients． The most frequently prescribed drugs were antiplatelet, statins and calcium channel blockers． The analysis of drugs used in treatment of a single disease showed that combined medication for hypertension was somewhat different from the recommended medication, while the prescriptions for coronary heart disease or hyperlipidem ia could meet the requirement of their secondary prevention． The nontherapeutic drugs, such as vitam ins, calcium tablets, blood circulation promoting and blood stasis removing herbals accounted for 9．3% of the totally used drugs． Conclusion Elderly outpatients suffer from several cardiovascular diseases and are usually treated with combined medications． D rugs prescribed in outpatient department accord with the evidence-based recommendation although they are somew hat different from those recommended in the guidelines and irrational use of drugs still exists．