Abstract: Objective Toobserve the effect of ultraviolet C combinedwith low-level laser therapy in promoting rapidhealing of infectedwounds and sinus after colon-cancer surgery. Methods The patient was a 48-year-oldmale with sigmoidcolon ulcer type differentiatedadenocarcinoma. A sinus about 3 cmwas foundat the endpart of operation incision after 3 weeks of laparoscopic radical resection of sigmoidcolon cancer. Debridement treatment was repeatedmany times, but the sinus was still difficult toheal. Then the patient was transferredtoour department. Ultraviolet C combinedwith laser radiation therapy was chosen. Firstly, iodophor alcohol was usedtoclean the woundand sinus. Secondly, low-level laser radiatedthe woundand sinus with the band of 660nm, the waveformof DC wave and the total power of 360 HW. Thirdly, the ultraviolet C irradiatedthe inside part of the sinus, the woundsurface and inflamedparts for once a day, a total of seven days. Results After seven days of light treatment, the sinus healedrapidly, the ulcer site were all curedwith scabs, and the redswelling area reducedsignificantly. Conclusion Ultraviolet C combinedwith low-level laser therapy can effectively promote healing of wounds and sinus after colon-cancer surgery.