Abstract: Objective To investigate the blood loss of precisedecompression and traditional standard laminectomydecompression in treatment of patients with lumbar spinal stenosis. Methods A retrospective study was carried out in 79 patients with lumbar spinal stenosis who were treated with precisedecompression or standard laminectomydecompression at Chinese PLA General Hospital from January 2011 to January 2012. Patients weredivided into two groups according to the surgery methods. Patients in group A (n=33) underwent precisedecompression and patients in group B (n=46) underwent standard laminectomydecompression. The general information, intraoperative, and postoperative blood loss (drainage), and blood infusion were recorded, and then, the visible blood loss (VBL), hidden blood loss (HBL) and total blood loss (TBL) were calculated. Results The mean visible blood loss, mean hidden blood loss and mean total blood loss in group A was (706±294) ml, (441±229) ml, (1 147±421) ml, and it was (762±394) ml, (565±204) ml, (1 327±452) ml in group B. There was significantdifference in hidden blood loss between group A and group B (P< 0.05). While, there was no statisticaldifference in total blood loss and visible blood loss between two groups (P> 0.05). Conclusion Precisedecompression leads to less hidden blood loss than that of standard laminectomydecompression.