Abstract: A bidirectional association exists between obstructive sleep apnea (OSA) and hypertension. OSA is a significant independent risk factor for hypertension, approximately 50% to 92% of OSA patients are complicated with hypertension, while 30% to 50% of hypertensive patients coexist with OSA. The treatment of OSA related hypertension is different from that of common hypertension, and both OSA and hypertension should be treated simultaneously. Lifestyle modification is the basis for the treatment of OSA associated hypertension. Continuous Positive Airway Pressure (CPAP), oral orthotics and surgical treatment are effective in management of OSA. In the treatment of hypertension, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are recommended drugs. Controlling volume overload with diuretics may be an effective treatment for OSA associated hypertension. Follow-up of blood pressure level, ventilatory therapy and other treatment methods are important in the management of OSA associated hypertension.