人羊膜修复肌腱损伤的研究进展

Research advances in tendon repair with human amniotic membrane

摘要: 肌腱粘连、肌腱愈合差导致的再断裂、腱骨不愈合是严重影响肌腱损伤修复术临床疗效的重要因素。人羊膜是一种胎盘内膜组织，富含多种生物活性物质及干细胞，具有预防肌腱粘连、促进肌腱及腱骨愈合的作用。人羊膜作为胎盘源性组织，免疫原性低，便于临床应用。本文就目前有关人羊膜在肌腱损伤修复方面的临床研究进行总结，并对未来发展进行展望。

Abstract: Tendon adhesion, rerupture and tendon bone nonunion due to poor tendon healing are important factors that seriously affect the prognosis. Human amniotic membrane, as a placental intima which is rich in a variety of bioactive substances and stem cells, can prevent tendon adhesion and promote tendon and tendon-to-bone healing. What's more, it is characterized by low immunogenicity, and easy to apply in clinical settings. This paper reviews clinical studies about human amniotic membrane using in the repair of tendon injury, and points out the future trend of its development.