Abstract: With the improvements of surgical devices and operative experience, laparoscopy-assisted total gastrectomy (LATG) gradually develops to totally laparoscopic total gastrectomy (TLTG), and the esophagojejunostomy is a key part of the operation. This review aims to sort out different methods of esophagojejunostomy in TLTG as well as their merits to provide references for clinical practice.