Research advances in sleep disturbance and related factors in patients with primary Sjögren's syndrome

Primary Sjögren's syndrome patients have a high prevalence of sleep disturbance with significant adverse effects and limited treatments, and it is associated with symptoms of the primary disease, laboratory indicators, and disorders such as anxiety, depression and obstructive sleep apnea. Its pathogenesis is still unclear. There are few researches on its correlation with systemic involvement and treatment. This article reviews the status quo of incidence and treatment of sleep disturbance in patients with primary Sjögren's syndrome, hoping to strengthen our understanding of it and provide reference for clinicians to identify this disease in the early stage.