Clinical significance of the level of blood glucose and insulin in old myocardial infarction

Objective: To investigate the changes of blood glucose and insulin after myocardial infarction. Methods: Oral glucose tolerance test （OGTT） and insulin release test was used to measure concentration of blood glucose and insulin before and after oral 75g glucose in 0h, 0.5h, 1h, 2h and 3h, were recorded in 52 subjects with old myocardial infarction（OMI） and 71 controls. HOMA IR and HOMA IS were calculated by Homeostasis model assessment（the Homa model）. Results: It was a high morbidity of diabetes （46.2%, P＜0.01） and lower insulin sensitivity （237.19162.35 vs 415.52272.64, P＜0.01） in old myocardial infarction. Significant glycaemia in 60min,120min,180min with post-glucose load in persons with OMI than controls, P＜0.01. The level og insulin in fasting,30 and 60min with post-glucose load secrete lower than conurols, P＜0.05. （Conclusion: ）There are abnormal levels of blood glucose and insulin with old myocardial infarction.