Inflammatory myofibroblastic tumor in genito-urinary system:A report of 14 cases

Objective To study the clinical characteristics,diagnosis and treatment of inflammatory myofibroblastic tumor（IMT） in genitor-urinary system. Methods Clinical data about 14 patients with IMT in genitor-urinary system（6 males and 8 females） at the age of 32 years（range 15-57 years） admitted to our hospital from January 2007 to December 2011 were retrospectively analyzed.Of the 14 patients,8 were diagnosed with cystic IMT with a diameter of 1.5-4.5cm（7 underwent transurethral resection of bladder tumor and 1 underwent partial cystectomy + ureterocysto-reimplantation）,3 were diagnosed with renal IMT with a diameter of 2-3.5cm（2 underwent enucleation and 1 received anti-inflammatory therapy）,1 was diagnosed with prostatic IMT and 1 was diagnosed with testis IMT（both received anti-inflammatory therapy）,and 1 was diagnosed with epididymis IMT（who underwent epididymectomy）. Results The patients were followed up for 3-50 months（mean 21 months）.Cystic tumor relapsed in 1 patient after operation.Although renal tumor did not recur in 2 patients after operation but recurred 5 months after anti-inflammatory therapy,which did not relapse after an additional 18-month anti-inflammatory therapy.Prostatic tumor relapsed 3 months after anti-inflammatory therapy and did not recur during the 20-month follow-up period.Testis and epididymis tumor did not recur after anti-inflammatory therapy. Conclusion IMT in genitor-urinary system is rare.Surgical transaction is the main choice of its treatment and a mall number of patients can be treated with anti-inflammatory therapy.