Effect of HLA-G5 on delayed graft function of kidneys

Objective To study the effect of HLA-G5 expression levels on delayed graft function (DGF) of kidneys． Methods Expression levels of HLA-G5 in kidney transplantation recipients were measured by ELISA． Effects of HLA-G5 expression levels on DGF of kidneys were comparatively analyzed． Results DGF did not occur in any kidney transplantation recipient with a high HLA-G5 expression level． However, the incidence of DGF was 57% in those with a low HLA-G5 expression level (P＜ 0．05)． Conclusion DGF is closely related with HLA-G5 expression level in kidney transplantation recipients． HLA-G5 can reduce the incidence of DGF by decreasing the reject reaction．