Establishment of small-size liver transplantation model for cirrhotic rats
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Abstract
Objective To establish the small-size liver transplantation model for cirrhotic rats. Methods Of the 24 SD cirrhotic rats,12 underwent small-size liver transplantation(56.3%) and 12 underwent whole liver transplantation(95.8%). Results The smallsize liver transplantation model was successfully established for cirrhotic rats.The liver function 24 h after operation and the 7-day survival rate were significantly higher in whole liver transplantation group than in small-size liver transplantation group(P<0.05). Conclusion The small-size liver transplantation model for cirrhotic rats can be used as an animal experiment platform for liver transplantation-related research.
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