Value of serum GRO-α level in assessing clinical prognosis of sepsis patients

Objective To study the value and role of GRO-αin assessing prognosis of sepsis patients. Methods Sixty-four sepsis patients admitted to ICU in our hospital from January 2011 to September 2012 were divided into survival group（n=31） and death group（n=33）, and 50 healthy subjects served as a control group. Their serum GRO- α and procalcitonin（PCT） levels were measured. The survival time of the 64 sepsis patients was analyzed. Results No significant difference was found in the GRO-α expression level although it was higher in survival group than in control group（P＞0.05）. The GRO- α expression level was significantly higher in death group than in survival group and control group（P＜0.05）. No significant difference was found in the serum PCT level between death group and survival group（P＞0.05）. The serum GRO-α level was not significantly related with the serum PCT level（P＞0.05）. Survival analysis showed that the survival time was shorter in sepsis patients with a high serum GRO-αlevel than in those with a low serum GRO-αlevel（P＜0.05）. Conclusion The serum GRO-αlevel in sepsis patients is closely related with their prognosis. The value of serum GRO-αlevel is higher than that of serum PCT level in predicting the survival rate and in assessing the prognosis of sepsis patients.