Analysis of drug sensitivity and distribution of pathogens in patients with urinary tract infections

Objective To analyze the drug sensitivity and distribution of pathogens in patients with urinary tract infections, and provide basis for clinical treatment of urinary tract infection. Methods From January 2014 to December 2014, the identification and drug sensitivity testing were performed simultaneously for Mycoplasma and bacteria were isolated from urine specimens that were obtained from the outpatients of nephropathy department. Results Of the 953 patients with urinary tract infection, 395 cases were positive in mycoplasma culture, with the positive rate of 41.45% and the susceptibility rate of more than 90% to Doxycycline and Minocycline; 154 cases were positive in bacterial culture, with the positive rate of 16.16%; 156 strains were isolated, and Escherichia coli was the main pathogen (71 strains, accounting for 45.51%), followed by Streptococcus viridans (14 strains, 8.97%), Enterococcus (12 strains, 7.69%), Klebsiella pneumonia (11 strains, 7.05%), Streptococcus agalactiae (11 strains, 7.05%). ESBL positive rates of Escherichia coli and Klebsiella pneumonia were 45.07% and 18.18%, respectively. No strains of Escherichia coli and Klebsiella pneumonia were found resistant to Imipenem or Meropenem, and no strains of Streptococcus viridans, Enterococcus, Streptococcus agalactiae were found resistant to Vancomycin or Linezolid. Conclusion Mycoplasma urealytium and Escherichia coli are the main pathogens in patients with urinary tract infection. Monitoring of species distribution and drug sensitivity characteristics of pathogens is important for the treatment of urinary infection diseases.