Distribution and antibiotic resistance of nosocomial urinary tract infection pathogens in department of hyperbaric oxygen

Objective To investigate the distribution and antibiotic resistance of pathogens isolated from the patients with urinary tract infections(UTI)in the department of hyperbaric oxygen(HBO)in our hospital from 2014 to 2018. Methods The pathogen species and antibiotic resistance data of the patients with UTI in the department of hyperbaric oxygen from 2014 to 2018 were retrospectively analyzed.All the samples were identified by VITEK 2 Compact of Biomerieux and MALDI-TOF MS of Bruker Daltonics,and the drug susceptibility tests were performed with MIC methods. Results There were 309 UTI cases in the HBO department within 5 years,and totally 362 strains(25 species)were isolated.Gram-negative bacteria,accounted for 71.82% of all the isolates,were the predominant pathogens.The proportions of Gram-positive bacteria and fungi were 17.13% and 11.05%,respectively.Escherichia coli,with the proportion of 24.03%,was the major pathogen among the Gram-negative bacteria and presented the lowest resistance rate to Nitrofurantoin(1.19%).Enterococcus Faecium,with the proportion of 8.56%,was the major pathogen among the Grampositive bacteria and had no resistance to Tigecycline.Candida albicans was the major pathogen among fungi(5.52%)and not resistant to Flucytosine,Fluconazole and Amphotericin B at all. Conclusion It is significant to guide clinicians performing empiric and preemptive therapy by regularly monitoring the distribution and antibiotic resistance of pathogens from the UTI patients in the HBO department.