Correlation between CT score and hs-CRP at different stages in COVID-19 patients

DENG Lanting; ZOU Yuyan; WANG Yan; DENG Quancheng; TIAN Ronghua

doi:10.3969/j.issn.2095-5227.2020.03.004

Volume 41 Issue 3

Mar. 2020

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ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL > 2020 > 41(3): 216-219. > DOI: 10.3969/j.issn.2095-5227.2020.03.004

DENG Lanting, ZOU Yuyan, WANG Yan, DENG Quancheng, TIAN Ronghua. Correlation between CT score and hs-CRP at different stages in COVID-19 patients[J]. ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL, 2020, 41(3): 216-219. DOI: 10.3969/j.issn.2095-5227.2020.03.004

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Correlation between CT score and hs-CRP at different stages in COVID-19 patients

Department of Medical Imaging, Xiaogan Central Hospital, Xiaogan 432000, Hubei Province, China

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Corresponding author:
TIAN Ronghua. Email: tianrh9999@163.com
Received Date: February 29, 2020
Available Online: July 06, 2021

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Objective To explore the value of chest CT score and hs-CRP in the staging diagnosis of COVID-19.
Methods Clinical data about 65 cases with confirmed COVID-19 admitted to our hospital from January to February in 2020 were retrospectively analyzed. They were divided into four groups according to the disease progression: stage 1 (0-3 days), stage 2 (4-7 days), stage 3 (8-14 days) and stage 4 (15-21 days). According to the clinical classification, the patients were divided into two groups: mild/moderate group and severe/critically ill group. CT score was calculated according to the extent of chest CT lesions, and the correlation between CT score and hs-CRP was analyzed.
Results Of the 65 cases, there were 33 males and 32 females, with an average age of 52.77±13.95 years. According to the disease progression, the CT score (stage 3 vs stage 1, stage 2, and stage 4: 11.27±2.02 vs 2.79±1.25, 6.40±1.32, 2.50±1.42) and hs-CRP value (stage 3 vs stage 1, stage 2, and stage 4: [81.61±63.46] mg/L vs [8.94±6.16] mg/L, [41.78±19.79] mg/L, [7.10±7.74] mg/L) in stage 3 were significantly higher than those in the other three stages (all P < 0.05). According to clinical classification, the CT score (12.05±1.75 vs 4.11±2.25) and serum hs-CRP value ([82.17±64.97] mg/L vs [25.01±21.77] mg/L) were higher in severe/critically ill patients than in mild/moderate patients (P < 0.05). There was a positive correlation between CT score and hs-CRP value (r=0.76, P=0.001).
Conclusion CT score combined with hs-CRP plays an important role in the diagnosis and dynamic evaluation of COVID-19.
- COVID-19,
- CT score,
- serum hypersensitive C-reactive protein,
- CT,
- severe pneumonia

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