Objective To analyze the application value of the point of care testing (POCT) in detecting urine myoglobin (Mb) in cadet during field training.
Methods We enrolled new cadets from one university who took part in field training from October 8, 2019 to October 19, 2019. All cases were male with mean age of 18 years. The serum and urine specimen in 65 cases were collected after the first day training and the last day training, and then the serum Mb and urine Mb were also compared between the first day training and the last day training. Serum creatine kinase (CK) was used as the standard of muscle damage to compare the sensitivity and accuracy of serum Mb and urine Mb after the first day training.
Results Totally 65 cadets were selected. All the cases were male with mean age of 18 years. Using POCT, urine Mb level of the last day decreased by 90.4% compared with the first day, with significant difference (P < 0.001). After first day training, serum CK is positive in 40 cases, serum Mb was positive in 2 cases, and urine Mb was positive in 19cases. The sensitivity of serum Mb was 5.0%, less than that of urine Mb (47.5%. P<0.001); the specificity of serum and urine Mb was 100%; and the accuracy of serum Mb was 41.5%, less than that of urine Mb (67.7%, P=0.003).
Conclusion Compared with the biochemical test of serum myoglobin, the POCT test of urine myoglobin have the advantages of high sensitivity and high accuracy. The urine sample is easy to obtain, and the POCT instrument is easy to carry. Therefore, testing urine Mb by POCT is worthy to apply in the monitoring of physical tstatus in field training.
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