Background Recent studies have showed that early enteral nutrition(EN) was associated with improved prognosis, but for those with contradictions, it might not be tolerated.
Objective To study the timing of enteral nutrition and explore the rational use of enteral nutrition for patients with severe acute pancreatitis.
Methods Data of SAP patients admitted to the Faculty of Hepato-Pancreato-Biliary Surgery, Chinese PLA General Hospital, and received enteral nutrition from January to December in 2019 were retrospectively collected and analyzed. The time of initiation of enteral nutrition, the tolerance after 72 hours and the effect of enteral nutrition in patients with SAP were collected, and the differences were compared between the success group and the failure group.
Results From January to December in 2019, 35 patients with SAP were enrolled, receiving 109 times of EN. Methods of feeding included oral and tube feeding, and the fomula covering multiple supplements such as monosaccharide, normal diet, etc. Among the 109 times of EN, 65 (59.63%) times were for male, 44 times were for female (40.37%), and their median age was 46 years (IQR: 36, 62). The success rate of EN was 71.6% (78/109). Multivariate logistic regression analysis showed body temperature>37.3℃(OR=0.07, 95% CI: 0.01, 0.27, P<0.001) were independent risk factor associated with the success of EN.
Conclusion Elevated body temperature was independent risk factors for diet intolerance.