Factors associated with non-healing wounds after brucellosis spondylitis

WEI Meng; LIU Hongzhou; WANG Lei

doi:10.3969/j.issn.2095-5227.2021.10.003

Volume 42 Issue 10

Oct. 2021

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ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL > 2021 > 42(10): 1020-1024. > DOI: 10.3969/j.issn.2095-5227.2021.10.003

WEI Meng, LIU Hongzhou, WANG Lei. Factors associated with non-healing wounds after brucellosis spondylitis[J]. ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL, 2021, 42(10): 1020-1024. DOI: 10.3969/j.issn.2095-5227.2021.10.003

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Factors associated with non-healing wounds after brucellosis spondylitis

1.
The Third Department of Orthopedics, Central Hospital of Handan City, Handan 056001, Hebei Province, China
2.
Department of Endocrinology, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
3.
Department of Orthopedics, the Fourth Medical Center, Chinese PLA General Hospital, Beijing 100048, China

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Corresponding author:
WANG Lei. Email: 307_wl@163.com
Received Date: February 24, 2021
Available Online: December 26, 2021

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Abstract

Background Brucella spondylitis is an infectious allergic disease caused by Brucella. Its treatment methods are mainly divided into surgical treatment for debridement and conservative drug treatment. For the surgical incisions of patients with Brucella spondylitis are non-clean incisions, the wound will not heal after surgery.
Objective To analyze the factors associated with postoperative non-healing wound in patients with brucellosis spondylitis, and provide evidence to reduce the incidence of postoperative non-healing wound in this disease.
Methods Totally 94 patients with Brucella spondylitis who underwent surgical treatment in our hospital from January 2013 to January 2018 were enrolled in this study. The patients' basic information and perioperative information were recorded. Multivariate logistic regression analysis was used to analyze the risk factors of wound non-healing in patients with Brucella spondylitis.
Results Of the 94 cases (54 males and 40 females, average age of 47.36±7.32 years old), wound non-healing was found in 13 patients (13.83%). Age (OR: 1.135, 95% CI: 1.032-1.248, P=0.009), combined diabetes (OR: 9.020, 95% CI: 1.294-62.885, P=0.026), extent of resection of involved site (OR: 20.911, 95% CI: 1.908-229.141, P=0.013) and blood albumin level (OR: 0.776, 95% CI: 0.664-0.907, P=0.001) were risk factors of postoperative non-healing wound in patients with Brucella spondylitis.
Conclusion Elderly patients, combined diabetes, incomplete resection of involved site and decreased blood albumin levels are risk factors for postoperative wound non-healing of Brucella spondylitis. Reasonable choice of surgical indications is the key to reduce incidence of wound non-healing after operation.
- spine,
- Brucellosis,
- surgery,
- wound non-healing,
- risk factor

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