Resection of benign liver lesions in the past 24 years:A retrospective analysis of 955 consecutive cases

Objective To analyze the operative and peri-operative factors related with resection of benign liver lesions and evaluate its reliability. Methods A total of 955 consecutive patients who underwent resection of benign liver lesions from January 1986 to December 2010 in Chinese PLA Air force General Hospital and Chinese PLA General Hospital were retrospectively analyzed. Results Hemangioma and hepatolithiasis were the most commonly encountered diseases in clinical practice,accounting for 44.3% of 423 patients and 27.7% of 265 patients with benign liver lesions.The blood loss was≤200ml in 596 cases（62.41%）,200-400ml in 122 cases（12.77%）,400-1 000ml in 164 cases（17.17%）,＞1 000ml in 73 cases（7.86%）.Three hundred and fifty-nine cases（37.59%） required transfusion of blood products during operation,81 cases（8.48%） were transfused with autoblood.The average operation time was（240.60±98.31）minutes,the average hospital stay time was（14.01±8.23）days after operation.The incidence of complications after operation was 13.72% and the peri-operative mortality was 0.21%.Multivariate analysis showed that the operation time was an independent factor for complications（P=0.003,OR=1.013） while the increased ALB was a protective factor for complications（P=0.035,OR=0.838）. Conclusion Resection of benign liver lesions is a safe procedure with a low incidence of death and complications when importance is attached to peri-operative management and innovation of surgical technique.