Effect of combined use of hyperthermia and MMC-C on human stomach low dif-ferentiatlon gland cancer cell line SGC-7901 in vitro

The stomach low differentiation gland cancer cell line(SGC-7901) which was set up by Shanghai sixth people Hospital was taken in this investigation. By using water-heating,we observed the effection of hyperthermia and MMC-C alone or combined use on the rule of checking the growth of cell and killing cell.
The results show that:1.Both hyperthermia and MMC-C can check the proliferation of the SGC-7901 cell and kill the cell directly. The effect on check of proliferation of the cell can be increased by using hyperthermia in combination with chemotherapy. 2.Hyperthermia in combination with MMC-C can check proliferaion or kill more cells than hyperthermia or the chemical drug used alone. But the killing effects of the sequences while heating and the chemical drug were being used simultaneously are the best.3.Being heated at 40℃ for an hour, the cell will grow up sharply. This result indicates that being heated alone with the temperature lower than 42℃ is unsuitable. 4.Heating temperature at 42℃ for an hour in combination with some suitable chemical drugs can get encouraging effect of cancer treatment.