Diagnosis and treatment gastric stromal tumor

Objective To study the diagnosis and treatment of gastric stromal tumor. Methods Diagnosis and treatment of 30 patients with gastric stromal tumor were retrospectively analyzed and biological behavior of the tumor was staged according to its potential malignancy. Results Gastric stromal tumor occurred in patients at the age of 37-75 years（mean age:55 years） with no difference in sex.The tumor was found at multiple sites,especially at the fundus and body of stomach,but rarely at antrum.The low,moderate and high malignancy of its biological behavior was 26.7%,23.3% and 50%,respectively.The patients had no specific clinical manifestations,but usually had bleeding in the upper digestive tract,pain in the middle and upper abdomen,and abdominal mass.Endoscopy could show the tumor mass in stomach,thus contributing to its early diagnosis confirmed by pathology and immunohistochemistry.Surgical operation remained the best procedure for it. Conclusion Gastric stromal tumor is an independent and non-directionally differentiated tumor.Gastroscopy and immunohistochemistry contribute to its early diagnosis.Operation should be performed immediately after its diagnosis is established.The patients should be followed up till to their end of life.