Coherent study of the therapeutic effects on chlamydia tracomatis or mycoplasma infection during pregnancy in relation to fetal growth

Objective: To find out the relationship between the therapeutic effects on tracomatis or mycoplasma infection during pregnancy and fetal growth. Methods: Cervical discharge from 600 pregnant women and the urethra secretion from the partners of those who were positive with C.trachomatis and Mycoplasma antigens by immunoflurescent method. The oral therapeutical doses of erythromycin given to the positive women and the occurrence of fetal abnormality, low weight birth, etc, were observed. And the relationships to whether their partners in fected were analyzed. Results: As compared with the untreated C.tracomatis infected group, rates of fetal abnormalities （abortion, stillbirth, deformity and new born death） and low weight births in the erythromycin-treated group were much lower （P＜0.05）. In the erythromycin-treated myeoplasma infected group, fetal abnormality rate was 13.1% （11/89） and low weight birgh rate 7.14%, but the difference was of no statistic significance. The curative effects on those women whose parthers were infected were poor. Conclusion: Erythromycin therapy may help reducing the occurrence of fetal abnormalities and low weight birth due to intrauterine C.trachomatis and mycoplasma infections during pregnancy. And the curative effects on the infected pregnant women are highhy related to whether their partners infected or not.