Disseminated mycosis in fetal liver transplantation——A cured case report

The patient was a femal, 11 years old, with B cell ALL CR₁. After conditioning with CY （cyclophosphamide） 50 mg/kgx2, DNR （daunorubicin） 30 mg x1, she received FLT （fetal liver transplantation） which was 600 ml suspension of 6 unrelated donor’s fetal liver. After FLT, on day 16, she developed fever, chills, skin rash, myodynia and arthrodynia, conjunctival congestion, megalohepatia, and jaundice, and SGPT levels raised up to 300 u/L （nv O-30u/L）. Ultrasonogram B and CT revealed bilateral renal multiple abscesses. Blood, bone marrow, urine, sputum, stool cultures all revealed candida （nonalbicans）. Sometimes, the sediments of unine contained black-gray masses, the examination of which showed large number of candida conolings and harpha. She was treated by a conbination of Amp B and 5-FC and Daktarin etc, and recovered. Follow-up for 1（1/2） year showed that the patient was still in CR and the complication of disseminated candida was cured eventually.