Therapeutic effect of renal artery revascularization on renal artery stenosis

Objective To observe the effect of renal artery angioplasty on blood pressure and kidney function in patients with renal artery stenosis（RAS）. Methods A total of 201 patients with RAS received percutaneous transluminal renal artery angioplasty/stents（PTRAS）. One hundred and thirty-eight patients were followed up for an average period of 13±10 months to observe changes occurred in their blood pressure,serum creatinine level,and glomerular filtration. Results Renal artery angioplasty was successfully performed in 96% of the 201 patients. The renal artery stenosis rate was decreased from 70%±11% to 12%±10% after PTRAS. The blood pressure of 138 followed-up patients was significantly decreased（P＜0.01）. The number of anti-hypertensive drugs was significantly decreased（P＜0.01）. The systolic blood pressure was decreased from（20.1±3.3） kPa to（18.3±2.1） kPa,while the diastolic systoli pressure was decreased from（10.9±2.010） kPa to（3±1.5） kPa. Instent restenosis occurred in 14 patients 1 to 23 months after operation,which was correlated with nonostial stenosis. Conclusion Patients with renal artery stenosis can benefit from PTRAS and instent restenosis is correlated with the type of RAS.