Changes of lipids and apolipoproteins in diabetes mellitus and hypertension and their effects

Objective:To investigate the changes of lipids and apolipoproteins in diabetes mellitus（DM） and hypertension（HT） and their effects.Methods:Testees were divided into 4 groups: control group,DM group,HT group,HT ＆ DM group.BMI was calculated;and cholesterol,triglyceride,high density lipoprotein（HDL）,Low density lipoprotein（LDL）,apolipoprotein（Apo） ApoA1,ApoA2,ApoB,ApoC2,ApoC3,ApoE.were tested on Roche H7600 chemistry analyzer.Results:there was difference on lipids and apolipoproteins by gender.ApoA2,ApoB,ApoC2,ApoC3,ApoE increased in HT group.And lower ApoA1,HDL in DM group.ApoC3 had a obvious change in DM compounding HT.ApoA2/C3 were related with the cause of HT.Compared with the normal,the DM and HT group had related lipids and apolipoproteins changes.Conclusion:Abnormal lipids and apolipoproteins metabolism indicate the development of diseases,which increase or decrease during the period of HT and DM.The dysfunction of lipids and apolipoproteins may affect the recovery from diseases if out of control.