Erythromelalgia accompanying polycythemia vera:A case report and review of the literature

Objective To study the mechanism,clinical manifestations and pathophysiological characteristics of erythromelalgia accompanying polycythemia vera. Methods Clinical manifestations,laboratory test and auxiliary examinations,autopsy report and platelet count of a patient with erythromelalgia were analyzed. Results The patient with a history of myeloproliferative disease developed extremity burning pain,painful erythema and even dry gangrene with formation of thrombosis in multiple systems and organs accompanying progressively decreased platelet count. Conclusion Formation of thrombosis is the major factor for the different clinical manifestations of erythromelalgia,which should be early diagnosed and treated with anti-platelet drugs.