Studies on the serum SARS-CoV（IgG）antibody level in 2132 cases of different population

Objective:to evaluate the clinical significance of the measurement of serum SARS-CoV（IgG）antibody.Methods:The serum SARS-CoV antibody have been measured in different population by both ELISA method and biochips technique，to analyze the difference between SARS and other diseaseas.Results:The positive rate of SARS-CoV（IgG）in convalescent SARS cases，nephropathy，cancer，pulmonary diseases，diabetes and other diseases were 75.6%（118/156）、29.3%（22/75）、22.3% （19/85）、22.7%（10/44）、13.6%（8/59） respectively，both 500healthy population and 500close contact medical staff in xiao tang shan hospital were negative ，which were measured by ELISA method.The biochips results indicated that convalescent - SARS cases have a positive rate of 86% and only 4 cases have positive SARS-CoV antibody in 62cases which have positive results by ELISA.Conclusion:Measurement of SARS-CoV antibody is a helpful marker to diagnosis recent SARS-associated coronavirus （SARS-CoV） infection.Biochips technique has better specificity and sensitivity than ELISA.