Distribution of cannabinoid receptor 2 expression in sarcoidosis and granuloma annulare tissues

Objective: To investigate the distribution of cannabinoid receptor 2（CB2） expressions in human normal skin,sarcoidosis,and granuloma annulare tissues. Methods: The distribution of CB2 expressions in human normal skin,sarcoidosis,and granuloma annulare tissues was detected with immunohistochemical staining. Results: The distribution of CB2 expression was observed in human skin,sarcoidosis and granuloma annulare tissues.CB2 was over expressed both in sarcoidosis tissue and in granuloma annulare tissue. Conclusion: CB2 expression of CB2 is closely related with sarcoidosis and granuloma annulare.