Effect of Zigui granule on intestinal immunobarrier in rat after scald

Objective: In ordr to protect the intestinal immunobarrier, Zigui granule （ZG） a complex of Chinese herbs was used to treat the burned rats.Methods:The burned rats were randomly divided into two groups:（1）ZG treated group feded with ZG: （2）control group: feded with 0.9% salime. Results:The levels of IgA in the intestinal content and the number of CD3 T lymphocytes in the lamina propria of the ZG groups were significantly increase （P＜0.05）, and the levels of plasma MDA and LPS were significantly lower than those of the control group （P＜0.05）.Conclusion:The results indicate that ZG may protect the inteastinal immunobarrier and prevent gut-derived endotoxemia after burn injury.