Autologous Bone Marrow Transplantation After Purging By Low Molecular Weight Natural Tumor Suppressor in Treatment of 13 Cases of Acute Leukemia

13 patients with acute leukemia （4 ALL and 9 ANLL patients） were treated by autologous bone marrow transplantation （ABMT）. Marrow grafts were previously purged by low molecular weight natural tumor suppressor （LMW-NTS）. Complete remissions resulted in 12 survival patients with ABMT after 6 months in 1, 122 months in 7 cases, and the remaining 4 cases relapsed in 3-6 months after ABMT. One patient died of marrow graft failure due to fungal septicemia on the 37th post ABMT day. The results indicated the hematopoietic recanstituts may be achived in these patients and the purging effect of LMW-NTS is encouraging us to carry further observation.