The study on antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae

Objective: To evaluate the antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae in vitro. Methods: Minimal inhibitory concentrations （MIC） were determined by dilution method according to NCCLs. Results: Moxifloxacin has the best antibacterial activity with the lowest MIC₉₀, Streptococcus pneumoniae （including Penicillin resistant Streptococcus pneumoniae） showed highest susceptibility to Moxifloxacin with 95.78% susceptible rate, susceptible rate of SIPA and ofloxacin was respectively. Conclusion: moxofloxacin has an powerful antibacterial activity against streptococcus pneumoniae and it can be the first choice to treat streptococcus pneumoniae infection.