Early diagnosis and treatment of multiple primary malignant tumors in the elderly

Objective: Experience of diagnosis for multiple primary malignant tumors（MPMTs) in early stage was summarized in order to give proper treatment in the elderly Methods: Seventy cases of MPMTs patients aged from 60 to 90 year old admitted to our hospital in the period of 1980 to 2002 were ananlyzed retrospectively There were 68 males and 2 femels fifty two cases of them had double primary malignant tumors and 18 cases had triple primary malignant tumors Results: Forty five cases,50 cases and 14 cases of them in the first, second and third primary malignant cancer were dignosed in early stage respectively There were 26 cases with double carcinoma and nine cases with triple cacer in the early stage thirteen cases with gastric carcinoma and bladder in early staging cancer were treated by endoscopic resection, of which median servival rate without cancer were 60 months（range,6 to 120 months) The 5-year survival rate for patients with MPMTs was 35 5% Twenty of forty six deaths were not directly tumor related Conclusion: Clinical symptem is not helpful for diagnosis of cancer in early stage Tumor marks, endoscopy and BUS were important procedure for early diagnoses of MPMTs Causes included sudden death, respiratory failure and upper gastrointestinal tract bleeding affect the 5-year servival rate of the patients with M PMTs