Study on Resistance to Antimicrobial Agents of MRSA

The morbidity of the infections caused hy MRSA was increased with years, in order to know the resistance to antimicrobial agents of MRSA, the minimum inhibitory concentrations （MICs） of antimicrobial agents against S. aureus isolated from patients and tested by B-lactamase and coagulase were measured. The results showed that MRSA was account for 50.7％ of the strains tested, the incidence of MRSA producing B-lactamase were 85.1％, the coagulase of MRSA Was type 1. MRSA showed multiple-resistance of most of B-lactam antibiotics and some aminoglycosides. Vancomycin and arbikacin had the highest activity against MRSA, the other drugs were in the follwing order: minocycline, amikacin, tosulfloxacin, imipenem and cloxacillin. It suggested that serious infections caused by MRSA may be cured by using the vancomycin, arbikacin or other drugs mentioned above.