Observation the effect of optic nerve incision decompression after optic nerve incomplete injuries

Objective: To evaluate the curative effect of a new style surgical management,optic nerve incision decompression（ONID）,for optic nerve incomplete injuries. Methods: By the use of reverse tweezer with invariable pressure,3 different degrees of rat optic nerve injury model were established and ONID was performed in various timing post-injury. The latency and amplitude of F-VEP were compared between ONID and non-ONID. Results: After ONID,the latency of F-VEP in mid-degree optic nerve injury showed significant decrease and the amplitude showed significant increase. Within 48,ONID got better results. While after ONID on mild and heavy-degree groups,the latencies retarded, the amplitudes reduced. Conclusion: By ONID,F-VEP of mid-degree optic nerve injuries can be obviously improved,but the effects of ONID on mild and heavy-degree groups are less,even negative. It is useful only within 48 hours after injury to reduce secondary optic nerve injury.