Effect of selective laser trabeculoplasty on intermediate and advanced primary open angle glaucoma

Objective To observe the effect of selective laser trabeculoplasty（SLT） on intermediate and advanced primary open angle glaucoma（POAG）. Methods SLT was performed for 23 patients（35 eyes） with uncontrolled intraocular pressure（IOP） after operation of intermediate and advanced POAG or topical drug treatment using a YAG laser therapy device.IOP,visual acuity,anterior chamber and complications were detected 1 hour,1 day,2 weeks,1 month,3 months and 6 months,respectively,after operation.Heidelberg retinal tomography-Ⅱ（HRT-Ⅱ） and visual field were checked 1 month,3 months and 6 months,respectively,after operation. Results The IOP was higher 1 hour after operation than before operation with a mean increase of 1.9mmHg（0.25kPa）.The IOP was lower 1 day,2 weeks,1 month,3 months and 6 months,respectively,post-operation than pre-operation with a mean decrease of 8.5mmHg（1.13kPa）,5.2mmHg（0.69kPa）,5.0mmHg（0.67kPa）,4.7mmHg（0.63kPa）,and 4.5mmHg（0.60kPa）,respectively（P＜0.000 1）. Conclusion SLT is an effective and safe procedure for intermediate and advanced POAG with uncontrolled IOP after operation or topical drug treatment,and can thus be used as a supplementary procedure.