The observation to different hemolysis influence to biochemistry assays results

Objective: to explore the influence of hemolysis to results of serum biochemistry assays.Methods:30 blood samples have been used which divided into three groups,including slight hemolysis（hemoglobin concentration was 0.8～3.0 g/L）,medium hemolysis（hemoglobin concentration was 3.1～5.0 g/L）,severe hemolysis（hemoglobin concentration was more than 5.0 g/L）.32 biochemistry parameters of serum with hemolysis and without hemolysis have been measured in parallel.ROCHE/HITACHI 7600 automatic biochemistry analyzer have been used for all of the tests.Results:Except ALP,GGT,LDL-C,TG,APOA-1,APOB,the results of other 26 biochemistry parameters had been interfered by hemolysis of the sample.（Conclusion:Hemolysis） could cause obvious false results of the serum biochemical parameters in hemoglobin dependent manner so that the hemolysis of sample have to be avoid in clinical work.