Intensive care combined with hydration therapy with sodium bicarbonate prevents contrastinduced renal damage in elderly patients after percutaneous coronary intervention

Objective To investigate the effect of intensive care combined with hydration therapy with sodium bicarbonate on contrast-induced renal damage in elderly patients after percutaneous coronary intervention（PCI）. Methods One hundred and nineteen patients who underwent PCI and hydrated therapy with sodium bicarbonate in our hospital from September 2008 to May 2009 were randomly assigned to intensive care group and conventional care group.Changes in serum creatinine were compared between the two groups. Results All the patients underwent intervention operation with no cardiovascular events occurred.Renal dysfunction was found in 1 patient of intensive care group and in 4 patients of conventional care group.The serum creatinine level was higher in intensive care group 24h after PCI than before PCI and significantly higher in conventional care group than in intensive care group 24h after PCI（P＜0.01）. Conclusion Intensive care combined with hydration therapy with sodium bicarbonate can prevent contrastinduced renal damage in elderly patients after PCI.