Studies on the conversion method between enzymatic and picric kinetic analysis of serum creatinine

Objective: To evaluate the discrepancy between Creatinine’s enzymatic method and picric kinetic method.Try to found the conversion equation to transfer the results between two methods.Methods:Measure creatinine’s results of 667 patients’ serum with two methods in parallel,then according to enzymatic method,divide the results into 5 level-groups.Averages,standard variances were compared.Results:It showed that all groups had good correlations with two methods（A:0.971,B:0.987,（C:0.950,）D:0.983,E:0.994）.Averages of 5 level-groups were calculated（A:64.0μmol/L,92.7μmol/L;B:182.5μmol/L,（201.9μmol/L）;C:（378.4μmol/L）,384.6μmol/L;D:561.2μmol/L,549.4μmol/L;E:1077.7μmol/L,1025.7μmol/L）.（Conclusion:Creatinine）’sresults with two methods could be switched by equations y（picric method）=0.9186x（enzymatic method）+34.385 and y（enzymatic method）=1.0872x（picric method）-37.065.