The pharmacokinetic study and clinic monitor of proxyphyline
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Abstract
The reversed phase HPCC was developed to determine the plasma concentration of proxyphyline in 5 healthy subjectis with a 400mg single dose of proxyphyline. The plasma concentration Was fitted with the Single compartment absorbtion model to con-time curve. The pharamacokintic parameters were obtained and the stable drug concentration in 30 subjects was monitored.
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