The role of signal intensity in stereotaxy for Parkinson’s disease

Objective: To investigate the role of signal intensity in stereotaxy for Parkinson’s disease. Methods: During the course of 14 microelectrode-guided selective thalamotomy and 43 pallidotomy for parkinson’s disease patients neuron discharge was recorded continuously. Signal intensity of all nuclens was computed and the cure of signal intensity-distance was ploted.It was compared signal intensity among the nucleus in Parkinson’s disease stereotaxy. Results: The signal intensity of different nucleus in thalamotomy is different The signal intensity of white matter was different from caudate nucleus and thalamencephal, At the same time the signal intensity of dorsal thalamus was different sharply from vim to several times. Theses differences were distinguished. The differences were more obvious when the distance-intensity cures were ploted on the other hand, although the signal intensity among nucleus in pallidotomy were different the difference were distinguished difficultly, because the cure of distance-intensity was fluctuated. Conclusion: Signal intensity can be a kind of localization method in thalamotomy but It was not good in pallidotomy.