Monitoring of antimicrobial resistance in our hospital in 2007

Objective To investigate the distribution of bacteria and monitoring of antimicrobial resistance in our hospital in 2007 in order to provide the scientific reference for clinical anti-infection therapy. Methods Antimicrobial susceptibility was tested with agar method,and the results of antimicrobial resistance monitoring were analyzed using the WHONET 5.4 software. Results A total of 1 502 bacterial strains were isolated in 2007. Of them,887 were gram-negative bacteria,402 were Gram-positive bacteria,and 213 were fungi. The sequence of common bacteria was pseudomonas aeruginosa（Pa）, escherichia coli,staptococcus epidermidis,staptococcus aurcus,klebesiella pneumoniae,enterococcus faecium and Acinetobacter baumanniis,with a corresponding isolated rate of 16.5%,13.5%,6.3%,5.8%,5.5%,4.4%,and 3.9%,respectively. The proportion of MRSA and MRSE was 57.9% and 96.4%,respectively. Vancomycin and teicoplanin resistant staphlococci were not isolated. The resistance rate of vancomycin and teicoplanin to staptococci was 1.8% and 3.6%,respectively. Gram-negative bacteria had the best sensitivity to IPM. Pseudomonas aeruginosa isolated from sputum specimens was the highest with an isolated rate of 24.0% and CAZ had the best sensitivity to IPM. Twenty-one escherichia coli strains were isolated from blood with a positive rate of 19.3%. Conclusion Antimicrobial resistance supervision should be strengthened,which can promote the reasonable use of antimicrobial agents.