A malignant tumar metastasing to hemopietic system

This article reported 13 cases malignant tumor metastasing to hemopoietic system in clinical characteritics of metastasts were bone pain, anemia, fever and hemorrhagic tendency. Spleno-megaly was absent in most of the cases and "dry aspiration" of bone marrow often occured. Laboratory findings include pancytopenia or anemia, associated with thrombocytopenia. Carcinoma cells were found in the peripheral blood and bone marrow. Necrosis or fibrosis of bone marrow was demonstrated under the light microscope.