Relationship between serum pancreatic polypeptide（PP）level and diabetic autonomous neuropathy

This paper presents the fluctuations of serum PP level before and after egg-meal in normalsubjects （NS） and diabetics.In patients≤50 years old （Group Ⅰ）,the basal PP level was notdifferent between NS-Ⅰ and diabetics without cardiac autonomous neuropathy （NDCAN-Ⅰ） or withcardiac autonomous neuropathy （DCAN-Ⅰ）.Whereas,the response to egg-meal in DCAN-Ⅰ was significantly lower than NS-Ⅰ and NDCAN-Ⅰ （P＜0.01 ＆ ＜0.05）,which was related to auton-omous neuropathy.In patients ＞50 years old （Group Ⅱ）,there was no statistical difference am-ong NS-Ⅱ,NDCAN-Ⅱ and DCAN-Ⅱ,except in NDCAN-Ⅱ,its PP levels before and after egg-meal were higher than NS-Ⅱ（P＜0.05）,which was of a nonspecific variation.It was believedthat serum PP was a useful biochemical index in the diagnosis of diabetic autonomous neuropa-thy.