Compare of several coral as bone graft substitute implanting mice cranial defects

Objective: This study was attempted to evaluate several coral biologic ability.Methods: Loose Porites lutea, compact Porites lutea, Porites pukonsis and Montipora sp. Cf. M implanted mice cranial critical size defects, The animals were sacrificed at 4,8,12 weeks respectively after operation and biologic ability was evaluated by histomorphometry, radiography and histology.Results: The degradate rate of compact Porites lutea was lower than other kinds of coral, and compact Porites lutea had good biocompatibility. Conclusion: compact Porites lutea will be a hopeful bone substitute to be used in repairing bone defect.