The influence of Chinese Tonifying Kidney Herbs upon the proliferative response and the membrane fluidity of peripheral blood mononuclear cells in 11 aged patients

Objective: The present paper was aimed to investigate the influence of Chinese traditional Tonifying Kidney Herbs （TKH） upon the proliferative response and the membrane fluidity of PBMC in the aged. Methods: Eleven aged patients with functional kidney deficiency were selected and treated with TKH. The proliferative response of PBMC to PHA by means of MTT before and after treatment, and the membrane fluidity of PBMC was tested by using DPH as fluorescent probe. Results: The proliferative response and membrane fluidity of PBMC were signicanfly improved after TKH treatment （P＜0.05） as compared with the controls. Conclusion: Chinese TKH may improve the cellular immunity of the aged with functional kidney deficiency by the possible way of enhancing the proliferative response and membrane fluidity of PBMC.