Therapy of central hyponatremia after surgery of craniopharyngioma

Objective: To study the clinical characterization and effective treatment of the patients with the water and blood sodium disorders after resection of craniopharyngioma and conclude the experiences of central hyponatremia in post-operative patients. Differentiate SIADH from CSWS.Methods: 30 post-opertive patients with central hyponatremia were retrospectively analyzed.Results: Hyponatremia, hydrouria and volume depletion were rectificated in all patients diagnosed as cerebral salt wasting syndrome. Conclusion: Central hyponatremia, especially CSWS are frequently seen after craniopharyngioma surgery. Hyponatremia, hypernatruria and variation of conscious state are diagnostic criteria of central hyponatremia. The appropriate treatment of cerebral salt wasting, fluid and salt replacement, is opposite from the usual treatment of hyponatremia caused by inappropriate secretion of antidiuretic hormone.