An animal model for the study on effects of repeated +Gz forces on temporomandibular joint

Objective: To analysis the effects of repeated +Gz forces on the temporomandibular joint（TMJ）, an animal model was established..Methods: 36 male Wistar rats were randomly divided into 3 groups, control group, +1Gz group, and +10Gz group.The control group was only fixed with rat-kept devices for 5 minutes.The +1Gz group was borne +1Gz for 5 minutes.The +10Gz group was repeatedly exposed +10Gz(each for 30s, onset rate about 0.5G/s, 5 times/d with +1Gz 1 minute intervals, 4d/wk, 3 Weeks in total..Results: The behaviors of these rats were described in details and pathologic injuries in TMJ were produced..Conclusion: The animal model, which has good repeatition and induces pathologic changes in different degrees under various experimental variables, is a perfect model to observe the effects of repeated +Gz stresses on TMJ.