Combined treatment of small cell lung cancer

46 patients with small cell lung cancer were treated with combined treatment.They were ofstage Ⅱ,Ⅲ,and Ⅳ including 8,14 and 24 cases respectively.Combined treatment consistedof chemotherapy,radiotherapy,chinese medicine,immuno-therapy and other adjuvant drugs.Gene-rally,the treatment started with chinese medicine and immunotherapy,and was followed with co-mbination chemotherapy （VCR,CTX,MTX and BCNU or CCNU etc） followed by radiotherapy.Inmajority continued chemotherapy lasted for more than 1 year in few cases even 3 to 5 years.In thestage Ⅱ,Ⅲ and Ⅳ,2-year survival rate was 6/7（85.7%）,4/11（36.4%） and 7/17（41.2%） res-pectively;and 5-year survival rate was 5/7（71.4%）,1/8（12.5%） and 0/11（0%） respectively.Wi-th duration of chemotherapy ≤16 weeks,the average survival in 37 patients was 17.3±9.4 months;with duration＞16 weeks,in 9 patients,it was 63.8+31.5months.There was significant dif-ference between them （t=4.386,p 0.001）.Authors stressed on necessity of effective chemotherap（?）for more than 2.5 years.