Helicobacter pylori infection rate in patients with peptic ulcer due to chronic hepatitis B and liver cirrhosis

Objective To study the correlation between helicobacter pylori（HP） infection and peptic ulcer due to chronic hepatitis B and liver cirrhosis. Methods HP infection was detected by gastroscopy,biopsy of gastric antrum mucosa tissue and rapid urease test.HP infection and peptic ulcer due to chronic hepatitis B and liver cirrhosis were comparatively analyzed. Results The positive HP infection rate of patients with peptic ulcer due to chronic hepatitis B and liver cirrhosis was 70% and 23.8%,respectively.Gastric ulcer and duodenal ulcer were detected in 47 and 113 of the patients with peptic ulcer due to chronic hepatitis B or liver cirrhosis with a positive HP rate of 10.6% and 94.7%,respectively,and in 68 and 16 of the patients with peptic ulcer due to combined hepatitis B and liver cirrhosis with a positive HP rate of 17.6% and 50%,respectively. Conclusion Duodenal ulcer due to chronic hepatitis B is related with HP infection while gastric ulcer due to chronic hepatitis B and liver cirrhosis is not significantly related with HP infection.