电阻抗断层成像技术在肺通气功能评估中的研究及应用

Research and application of Electrical Impedance Tomography in pulmonary ventilation function assessment

  • 摘要: 肺通气功能评估对呼吸系统疾病严重程度评价、病情进展监测、疾病预后及疗效评估至关重要。为了更深入地揭示疾病的复杂性和异质性,需要从单一评估肺部整体功能转向同时考量肺部各区域的通气状态,但目前以肺活量测定法为主的肺功能测试(pulmonary function test,PFT)并不能提供区域的肺通气功能信息。电阻抗断层成像技术(electrical impedance tomography,EIT)是一种新兴的功能性、无辐射成像技术,可通过实时监测肺部区域的通气变化来评估区域肺功能。尽管该技术已经显示出预测肺功能测试指标的潜力,但在更广泛的临床环境中,对于肺功能评估的有效性和准确性仍需进一步验证。本文就EIT在肺通气功能评估中的研究及应用作一综述,以期为EIT在临床中的应用与研究提供更多的探索方向。

     

    Abstract: Pulmonary ventilation function assessment is very important for the severity evaluation, disease progression monitoring, disease prognosis and efficacy evaluation of respiratory diseases, which is highly valued by clinicians. With the deepening of the understanding of the disease, we need to pay attention not only to the overall pulmonary function, but also to the level of pulmonary ventilation function in different regions of the lung. However, the current pulmonary function test (PFT) based on spirometry cannot provide regional lung function information. Pulmonary electrical impedance tomography (EIT) is an emerging functional, non-radiation imaging technology, which can evaluate regional lung function by monitoring the ventilation changes in the lung in real time. Although this technique has shown the potential to predict pulmonary function test indicators, its validity and accuracy in the assessment of pulmonary function in a broader clinical setting need to be further validated.This article reviews the research and application of EIT in pulmonary ventilation function assessment, in order to provide more exploration directions for the application and research of EIT in clinical practice.

     

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